About Trulance

Managing irritable bowel syndrome with constipation (IBS-C) or chronic idiopathic constipation (CIC) can be a challenge. But whether you’ve just been diagnosed with IBS-C or CIC or have been dealing with it for a while, one thing is for sure: when managing constipation, your goal should be more regular, well-formed bowel movements with less IBS-C related abdominal pain and bloating.*

Why Trulance?

Trulance is a prescription medicine used in adults to treat IBS-C or CIC. It can help provide more regular, well-formed bowel movements with less IBS-C related stomach pain and bloating.*

*In clinical studies, greater improvements in abdominal pain and bloating were seen with Trulance as compared to placebo. Changes in abdominal symptoms such as bloating were measured separately from relief of abdominal pain and constipation.

TRULANCE FOR CIC  TRULANCE FOR IBS-C 

How it works

Trulance is the only medication for IBS-C and CIC that is nearly identical to uroguanylin (yur-oh-gwah-nih-lin),* a peptide (building block of protein) that occurs naturally in your body.

HOW TRULANCE WORKS 

Taking Trulance

Trulance is a once-daily medication for adults with IBS-C or CIC.

HOW TO TAKE TRULANCE  

Common side effects

The safety of Trulance has been well studied.

SAFETY OF TRULANCE 

The American College of Gastroenterology (ACG), one of the leading organizations of gastroenterologists, has given Trulance, as part of a class of drugs, a strong recommendation to treat global IBS-C symptoms. This is based on the highest level of clinical trial data.

If you want to learn more about the clinical data supporting the recommendation to see if Trulance is right for you, talk to your doctor.

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What Is Trulance?

Trulance® (plecanatide) 3 mg tablets is a prescription medicine used in adults to treat Irritable Bowel Syndrome with Constipation (IBS-C) and Chronic Idiopathic Constipation (CIC). Chronic means the constipation is long lasting. “Idiopathic” means the cause of the constipation is unknown. It is not known if Trulance is safe and effective in children less than 18 years of age.

What is the most important information I should know about Trulance?

  • Do not give Trulance to children who are less than 6 years of age. It may harm them.
  • You should not give Trulance to children 6 years to less than 18 years of age. It may harm them.
  • Do not take Trulance if a doctor has told you that you have a bowel blockage (intestinal obstruction).

What Is Trulance?

What is the most important information I should know about Trulance?

  • Do not give Trulance to children who are less than 6 years of age. It may harm them.
  • You should not give Trulance to children 6 years to less than 18 years of age. It may harm them.
  • Do not take Trulance if a doctor has told you that you have a bowel blockage (intestinal obstruction).
See Less

What Is Trulance?

Trulance® (plecanatide) 3 mg tablets is a prescription medicine used in adults to treat Irritable Bowel Syndrome with Constipation (IBS-C) and Chronic Idiopathic Constipation (CIC). Chronic means the constipation is long lasting. “Idiopathic” means the cause of the constipation is unknown. It is not known if Trulance is safe and effective in children less than 18 years of age.

What is the most important information I should know about Trulance?

  • Do not give Trulance to children who are less than 6 years of age. It may harm them.
  • You should not give Trulance to children 6 years to less than 18 years of age. It may harm them.
  • Do not take Trulance if a doctor has told you that you have a bowel blockage (intestinal obstruction).

Before you take Trulance, tell your doctor:

  • If you have any other medical conditions.
  • If you are pregnant or plan to become pregnant. It is not known if Trulance will harm your unborn baby.
  • If you are breastfeeding or plan to breastfeed. It is not known if Trulance passes into your breast milk. Talk with your doctor about the best way to feed your baby if you take Trulance.
  • About all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the common side effects of Trulance?

Diarrhea is the most common side effect and can sometimes be severe. Diarrhea often begins within the first 4 weeks of Trulance treatment. Stop taking Trulance and call your doctor right away if you get severe diarrhea.

These are not all the possible side effects of Trulance. Call your doctor for medical advice about side effects.

You are encouraged to report side effects to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For product information, adverse event reports, and product complaint reports, please contact:

Salix Product Information Call Center

Phone: 1-800-321-4576

Fax: 1-510-595-8183

Please click here for full Prescribing Information for Trulance, including Medication Guide and BOXED WARNING.

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